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KMID : 0387420200310010049
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Korean Society of Oriental Neuropsychiatry
2020 Volume.31 No. 1 p.49 ~ p.61
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Review of Clinical Studies on the Treatment of Menopausal Depression Using Traditional Chinese Medicine -Focusing on Randomized Controlled Trial in CNKI
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Choi Sung-Ryul
Jung Sung-Yub
Hong Doo-Hyun
Yu Jin-Sil
Choi Jong-Ho
Kim Mi-Hye
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Abstract
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Objectives: The objective of this study is to analyze clinical reports of treatment of menopausal depres-sion in traditional Chinese medicine (TCM).
Methods: This study included randomized controlled trials (RCT) in treating menopausal depression. Literature studies of Chinese National Knowledge Infrastructure Database(CNKI) were performed. Clinical reports on menopausal depression treatment were searched using the following key words in the CNKI: ‘menopausal depression’ and ‘postmenopausal depression’.
Results and Conclusions: A total of 24 RCT articles on menopausal depression were selected. The most widely used diagnostic tool for menopausal depression was CCMD-3. Effective rate and HAMD were the most commonly used assessment tools. Bosinhaeultang-gagam (Bushenjieyu-tang jiajian) and Gami-gammaegdaejotang(Jiawei ganmaidazao-tang) were used much more than other prescriptions, while Bupleuri Radix was the most used single medicine herb. Additionally, the Chinese medicine treat-ment group showed less adverse reactions than the control group. As a result, we could know fre-quently used herbal prescription and single medicinal herbs and this can be helpful in developing more advanced studies in future.
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KEYWORD
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Menopausal depression, Postmenopausal depression, Traditional Chinese Medicine (TCM), Herb medicine
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